Stephan E. Lehnart

Development of a protein synthesis network at the sarco/endoplasmic reticulum in adult cardiac myocytes

The paper examines the relationship between the ER and SR in cardiac myocytes, finding that the SR becomes the primary site of protein synthesis in adult cells, while the ER retains specialized functions.

Establishing synthetic ribbon-type active zones in a heterologous expression system

The paper reconstitutes synthetic ribbon-type active zones in HEK293 cells using Bassoon, RIBEYE, and CaV1.3 channels, showing structural and functional similarities to native ribbons.

Sarcomere analysis in human cardiomyocytes by computing radial frequency spectra

This paper introduces a computational method to analyze sarcomere properties in human cardiomyocytes using radial frequency spectra, showing its effectiveness in detecting molecular differences in cardiac diseases.

A versatile microfluidics platform for enhanced multi-target super-resolution microscopy

This paper introduces a microfluidics platform for multiplexed super-resolution microscopy, demonstrating its use in imaging cancer and cardiac cells with high reproducibility.

Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14Delta/+ mice hearts

mini-Complexome Profiling (mCP), an FDR-controlled workflow for global targeted detection of protein complexes

The paper introduces mCP, a streamlined workflow for detecting protein complexes with reduced fractionation, and demonstrates its application in analyzing cardiac tissue.