GeneticsNature GeneticsPeer-reviewed
A comprehensive portrait of cilia and ciliopathies from a CRISPR-based screen for Hedgehog signaling
David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp…·Maxence V. Nachury
This study uses a CRISPR-based screen to identify genes critical for Hedgehog signaling and ciliary function, revealing novel components of ciliary structures and linking congenital heart defects to ciliopathies.
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