David K. Breslow

This study identifies a phospho-regulatory module involving PPP2R3C and MAP3K1 that regulates centrosome function and is linked to congenital syndromes with gonadal dysgenesis.

This study uses a CRISPR-based screen to identify genes critical for Hedgehog signaling and ciliary function, revealing novel components of ciliary structures and linking congenital heart defects to ciliopathies.