Siddharth Neog

Single-cell transcriptomics resolves the developmental transitions from schizont to invasive extracellular merozoite to ring-stage Plasmodium falciparum parasites

This study uses single-cell RNA sequencing to map the transcriptional changes during the transition from schizont to merozoite to ring-stage Plasmodium falciparum parasites, revealing gene expression patterns related to egress, invasion, and intracellular survival.

The N-terminal region of malaria vaccine candidate Plasmodium falciparum asparagine-rich merozoite antigen is immunodominant and targeted by polyreactive antibodies

This study investigates B cell and antibody responses to PfARMA, finding that IgM and IgG predominantly target the N-terminal IDR1 region, but these responses do not correlate with protection against malaria.