Silvia Russi

Conformational flexibility of soybean lipoxygenase is coupled to crystal solvent content in serial crystallography

This study determines two distinct structures of soybean lipoxygenase-1 from a single experiment, showing that conformational flexibility is influenced by crystal solvent content.

CAGE-TRX expands the scope of time-resolved crystallography through genetically encoded active-site photocaging

The paper introduces CAGE-TRX, a method for time-resolved crystallography that uses photocaged amino acids to control enzyme activity and capture reaction intermediates.

Time-Resolved Crystallography Reveals the Mechanisms of GTP hydrolysis for N-RAS and the Oncogenic Mutants G12C, G12V and Q61L

This study uses time-resolved crystallography to capture GTP hydrolysis intermediates of N-RAS and oncogenic mutants, revealing shared and distinct reaction mechanisms.

Novel polymer fixed-target microfluidic platforms with an ultra-thin moisture barrier for serial macromolecular crystallography

This paper introduces a polymer film technology for serial macromolecular crystallography that provides an efficient hydration barrier and low X-ray background.

An investigation on the feasibility of shipping protein crystals in plates for room temperature in situ data collection

This study shows that shipping protein crystals at room temperature across long distances does not compromise diffraction quality for in situ X-ray diffraction experiments.

Scalable Fabrication of an Array-Type Fixed-Target Device for Automated Room Temperature X-ray Protein Crystallography

This paper describes a scalable microfluidic device for automated X-ray crystallography that enables efficient and damage-free crystal mounting for protein structure analysis.