BiochemistryProtein SciencePeer-reviewed
Small heat shock proteins HspB1 and HspB5 differentially alter the condensation and aggregation of the TDP-43 low complexity domain
Thomas B. Walker, Joshua W. Trowbridge, Shannon McMahon…·Luke McAlary
This paper shows that HspB1 and HspB5 differentially regulate TDP-43LCD condensation and aggregation, with HspB1 increasing dynamic exchange and HspB5 delaying pathological transition.
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