Author

Joseph Sarsam

University of California San DiegoORCID 0009-0002-7550-3035Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Alexandra T. TankkaiD· 1 shared Catherine J. Zhou· 1 shared Corina E. AntaliD· 1 shared Dan S. KaufmaniD· 1 shared Frederick E. TaniD· 1 shared Gene Wei-Ming YeoiD· 1 shared Grady G. NguyeniD· 1 shared Jack T. NaritomiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexandra T. TankkaORCID

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1 paper

Recent·Most cited

Integrative CRISPR Screens and RNA-Omics Discover an Essential Role for PUF60-3' Splice Site Interactions in Cancer Progression

Alexandra T. Tankka, Jaclyn M. Einstein, Catherine J. Zhou, Vivian N. Pham, Yuhan Zhang, Jack T. Naritomi, Grady G. Nguyen, Orel Mizrahi, Mark Perelis, Joseph Sarsam, Frederick E. Tan, Dan S. Kaufman, Corina E. Antal, Gene Wei-Ming Yeo

The paper identifies PUF60's role in cancer progression by combining CRISPR screens and RNA-omics, showing its splicing activity supports TNBC proliferation and is a potential therapeutic target.

bioRxiv · May 1, 2025 · PreprintCancer Biology