MicrobiologyPLoS BiologyPeer-reviewed
A genome-wide genetic screen identified targets for destabilizing the parasitophorous vacuole of Chlamydia trachomatis
Mohammed Rizwan Babu Sait, Lana H. Jachmann, Gözde Türköz…·Barbara Susanne Sixt
The paper identifies CpoS as a key effector for maintaining Chlamydia trachomatis vacuole integrity by regulating sphingolipid supply and shows that disrupting this pathway can clear infection without harming host cells.
4 citations