Author

Barbara Susanne Sixt

Umeå Centre for Microbial ResearchORCID 0000-0002-5607-8902Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Assay:proteomics· 1

Frequent Co-Authors

Anastasiia ChabaniD· 1 shared Astrid CollingroiD· 1 shared Bernhard SchmiereriD· 1 shared Burkhard KleuseriD· 1 shared Celia Llorente-SáeziD· 1 shared Elena Rebecca ToenshoffiD· 1 shared Fabian SchumacheriD· 1 shared Frederik HendrickxiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Anastasiia ChabanORCID

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2 papers

Recent·Most cited

A genome-wide genetic screen identified targets for destabilizing the parasitophorous vacuole of Chlamydia trachomatis

Mohammed Rizwan Babu Sait, Lana H. Jachmann, Gözde Türköz, Milica Milivojevic, Celia Llorente-Sáez, Soniya Dhanjal, Fabian Schumacher, Sara Henriksson, Naga Venkata Gayathri Vegesna, Noha Seddik, Anastasiia Chaban, Partha Mohanty, Magnus Ölander, Samada Muraleedharan, Sepideh Farmand Azadeh, , Barbara Susanne Sixt

The paper identifies CpoS as a key effector for maintaining Chlamydia trachomatis vacuole integrity by regulating sphingolipid supply and shows that disrupting this pathway can clear infection without harming host cells.

PLoS Biology · Aug 12, 2025Peer-reviewedMicrobiology

Ecology and evolution of chlamydial symbionts of arthropods

Tamara Halter, Stephan Köstlbacher, Astrid Collingro, Barbara Susanne Sixt, Elena Rebecca Toenshoff, Frederik Hendrickx, Rok Kostanjšek, Matthias Horn

The paper analyzes the ecology, evolution, and genomic diversity of Rhabdochlamydiaceae, a chlamydial family infecting arthropods, revealing genome reduction and transposable element dynamics.

ISME Communications · May 24, 2022Peer-reviewedGenomics