The paper investigates how tau accumulation in the entorhinal cortex affects episodic memory by analyzing grid-cell-like signals in older adults using MRI and tau PET.

bioRxiv · Sep 1, 2026 · PreprintNeuroscience

Mesoscale medial temporal lobe connectivity patterns relate to tau pathology and memory in older adults

Larissa Fischer, Niklas Vockert, Joseph Höpker Fernandes, Berta Garcia‐Garcia, Sebastian Niclas Roemer, Nicolai Franzmeier, Helena Marie Gellersen, Beate Schumann‐Werner, Niklas Behrenbruch, Svenja Schwarck, Eóin N. Molloy, Gusalija Behnisch, Constanze I. Seidenbecher, Björn Hendrik Schott, Bárbara Morgado, , Anne Maaß

This study examines how mesoscale connectivity patterns in the medial temporal lobe relate to tau pathology and memory in older adults, finding distinct associations with age and AD pathology.

bioRxiv · Aug 21, 2026 · PreprintNeuroscience

The in-vivo microstructural profile of human hippocampal subfield CA1 and its relation to memory performance

Dayana Hayek, Joseph Höpker Fernandes, Niklas Vockert, Berta Garcia‐Garcia, Hendrik Mattern, Niklas Behrenbruch, Larissa Fischer, Avinash Kalyani, Juliane Doehler, Dorothea Hämmerer, Yeo‐Jin Yi, Stefanie Schreiber, Anne Maass, Esther Kuehn

This study uses 7 Tesla MRI to examine depth-dependent myelination patterns in hippocampal CA1 and links them to memory performance in younger adults.

Human Brain Mapping · May 1, 2026Peer-reviewedNeuroscience