This study examines how mesoscale connectivity patterns in the medial temporal lobe relate to tau pathology and memory in older adults, finding distinct associations with age and AD pathology.

bioRxiv · Aug 21, 2026 · PreprintNeuroscience

Hippocampal-cortical connectivity relates to inter-individual differences and training gains in distinguishing similar memories

Panagiotis Iliopoulos, Jeremie Güsten, Eóin N. Molloy, Radoslaw Martin Cichy, Friedrich Krohn, Anne Maass, Emrah Düzel

This study examines how hippocampal-cortical connectivity relates to individual differences and training gains in mnemonic discrimination.

Communications Biology · Dec 27, 2025Peer-reviewedNeuroscience

Harmonized Protocol for Segmentation of the Hippocampal Tail on High-Resolution in vivo MRI from the Hippocampal Subfields Group (HSG)

Robin de Florès, Kelsey L. Canada, Thackery I. Brown, Nicole J Gervais, Anne Maaß, Gustaf Rådman, Jonathan P. Shine, Hannah L. Tucker, Eóin N. Molloy, Jenna N. Adams, Michelle Baca Reinke, Arnold Bakker, David Berron, Marshall Axel Dalton, Kristen M. Kennedy, , the Alzheimer’s Disease Neuroimaging Initiative

The paper presents a harmonized segmentation protocol for the hippocampal tail in high-resolution MRI, improving cross-study comparability through standardized definitions and consensus-based guidelines.

bioRxiv · Nov 20, 2025 · PreprintNeuroscience

Longitudinal functional connectivity during rest and task is differentially related to Alzheimer's pathology and episodic memory in older adults

Larissa Fischer, Jenna N. Adams, Eóin N. Molloy, Jennifer Tremblay‐Mercier, Jordana Remz, Alexa Pichet Binette, Maria Natasha Rajah, Sylvia Villeneuve, Anne Maaß, Judes Poirier, John C.S. Breitner, Mohamed Badawy, Sylvain Baillet, Andrée‐Ann Baril, Pierre Bellec, , Robert Jr Laforce

The paper examines how changes in functional connectivity during rest and task relate to Alzheimer's pathology and episodic memory in older adults.

Scientific Reports · Nov 4, 2025Peer-reviewedNeuroscience

Differential effects of aging, Alzheimer's pathology, and APOE4 on longitudinal functional connectivity and episodic memory in older adults

Larissa Fischer, Jenna N. Adams, Eóin N. Molloy, Niklas Vockert, Jennifer Tremblay‐Mercier, Jordana Remz, Alexa Pichet Binette, Sylvia Villeneuve, Anne Maaß

The paper examines how aging, Alzheimer's pathology, and APOE4 genotype affect longitudinal functional connectivity and episodic memory in older adults.

Alzheimer s Research & Therapy · Apr 24, 2025Peer-reviewedNeuroscience

Precuneus activity during retrieval is positively associated with amyloid burden in cognitively normal older APOE4 carriers

Larissa Fischer, Eóin N. Molloy, Alexa Pichet Binette, Niklas Vockert, Jonas Marquardt, Andrea Pacha Pilar, Michael Christoph Kreissl, Jordana Remz, Jennifer Tremblay‐Mercier, Judes Poirier, Maria Natasha Rajah, Sylvia Villeneuve, Anne Maaß

The paper examines how precuneus activity during memory retrieval relates to future amyloid burden and cognitive outcomes in APOE4 carriers and non-carriers.

Journal of Neuroscience · Jan 9, 2025Peer-reviewedNeuroscience

One-week escitalopram intake shifts excitation-inhibition balance in the healthy female brain

Rachel G. Zsido, Eóin N. Molloy, Elena Čėsnaitė, Gergana Zheleva, Nathalie Beinhölzl, Ulrike Scharrer, Fabian A. Piecha, Ralf Regenthal, Arno Villringer, Vadim V. Nikulin, Julia Sacher

This study shows that one week of escitalopram intake in healthy females shifts cortical excitation-inhibition balance toward excitation, as indicated by decreased 1/f slope.

bioRxiv · Jul 9, 2021 · PreprintNeuroscience