Author

Hyun Kyoung Lee

Baylor College of MedicineORCID 0000-0002-9568-5043Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

Askar M. AkimzhanoviD· 1 shared Carlo D. CristobaliD· 1 shared Chihiro HashiomotoiD· 1 shared Chorong Han· 1 shared Fransisca LeonardiD· 1 shared Han Nhat Tran· 1 shared Hui DengiD· 1 shared Ji Ye Lim· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

Askar M. AkimzhanovORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

DHHC3-dependent S-Acylation of CRY1 regulates its subcellular localization and repressor function in the circadian clock

Ji Ye Lim, Shayahati Bieerkehazhi, Chorong Han, Sun Young Kim, Matthew L. Baker, Tingting W. Mills, Kuang‐Lei Tsai, Hyun Kyoung Lee, Sung Yun Jung, Zheng Chen, Askar M. Akimzhanov, Seung Hee Yoo

This study identifies S-acylation of CRY1 as a critical post-translational modification regulated by DHHC3, essential for its nuclear localization and repressor function in the circadian clock.

bioRxiv · May 22, 2026 · PreprintBiochemistry

Combined inhibition of S100A4 and TIGIT suppresses late-stage breast cancer metastasis to the lung by activating T and NK cells

Jia-Shiun Leu, Hui Deng, Han Nhat Tran, Wei Xiong, Nourhan Abdelfattah, Thomas K. S. Wong, Reece Kang, Chihiro Hashiomoto, Fransisca Leonard, Sinem Gunalp, José M. Benítez Salazar, José Maldonado, Carlo D. Cristobal, Hyun Kyoung Lee, Zhiqiang An, , Kyuson Yun

This study shows that combining S100A4 and TIGIT inhibition suppresses breast cancer lung metastasis by enhancing T and NK cell activity in late-stage disease.

Cancer Letters · Apr 8, 2026Peer-reviewedCancer Biology