Tong Chen

This study identifies RBM6 as a host factor that enhances EA H1N1 SIV replication through alternative splicing at the M901 site, with implications for viral adaptation and interspecies transmission.

This study identifies lactylation of the influenza virus polymerase acidic protein (PA) as a novel mechanism enhancing viral replication and pathogenicity through host enzymes ATAT1 and SIRT1.

This study identifies GGCX as a key factor enabling EA H1N1 SIV adaptation to human-type -2,6 sialic acid receptors through HA carboxylation, suggesting it as a potential antiviral target.