Hongbo Zhou

This study determines the structure of PEDV S1B bound by neutralizing and non-neutralizing antibodies, revealing how C62 targets a conserved epitope and influences viral entry and neutralization.

This study identifies lactylation of the influenza virus polymerase acidic protein (PA) as a novel mechanism enhancing viral replication and pathogenicity through host enzymes ATAT1 and SIRT1.

This study identifies GGCX as a key factor enabling EA H1N1 SIV adaptation to human-type -2,6 sialic acid receptors through HA carboxylation, suggesting it as a potential antiviral target.