A resource to enable chemical biology and drug discovery of WDR Proteins
Suzanne Z. Ackloo, Fengling Li, Magda Szewczyk, Almagul Seitova, P. Loppnau, Hong Zeng, Jin Hua Xu, Shabbir Ahmad, Yelena A. Arnautova, Arrash J. Baghaie, Serap Beldar, Albina Bolotokova, Paolo A. Centrella, Irene Chau, Matthew A. Clark, , C. H. Arrowsmith
The paper develops a resource for discovering ligands for WDR proteins using experimental and computational methods, leading to the identification of drug-like ligands for 9 out of 20 targets.
Journal of Medicinal Chemistry · Nov 4, 2024Peer-reviewedBiochemistry