Simon Graf

This study identifies sex-dimorphic molecular responses to microglial depletion in aged mice, highlighting differences in transcriptional and proteomic changes between males and females.

This study benchmarks large language models for classifying pathogen-disease associations in post-acute infection syndromes using PubMed abstracts.

This paper uses VINE-seq to create a vascular transcriptomic atlas in Alzheimer's disease, revealing transcriptional changes in vascular cells and identifying angiopoietin signaling as a key dysregulated pathway.

The paper uses single-cell spatial transcriptomics to analyze brain samples from neurodegenerative diseases and COVID-19, identifying disease-specific transcriptional patterns and microenvironmental changes.

The paper constructs a multimodal brain cell atlas of adult macaques across their lifespan, revealing aging-related molecular changes and identifying aging hotspots and regulatory loci.

This study uses spatial transcriptomics to compare aging and infection effects across multiple organs in mice, identifying shared gene expression patterns in immune pathways.

ABC-HuMi catalogs 19,218 biosynthetic gene clusters from the human microbiome, offering a comprehensive resource for exploring bioactive compound potential.