Author

Daniel Hicks

University of Southern CaliforniaORCID 0009-0003-0314-8481Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Adam J. HrubyiD· 3 shared Aeowynn J. CoakleyiD· 3 shared Athena AlcalaiD· 3 shared Gilberto GarciaiD· 3 shared Maxim AverbukhiD· 3 shared Naibedya Dutta· 3 shared Ryo Higuchi‐SanabriaiD· 3 shared Andrew Bong· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

Adam J. HrubyORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintOct 31, 2026

✦ In-depth digest

Expression of tardigrade intrinsically disordered proteins in C. elegans reveals variable effects on aging and stress

Anna Entin, Daniel Hicks, Elijah A. Roditi…·Ryo Higuchi‐Sanabria

Constitutive somatic expression of four tardigrade disordered proteins shortened C. elegans lifespan and healthspan and gave little stress protection. Three of the four reduced polyQ aggregation under hyperosmotic stress.

DOI 10.64898/2026.10.26.762026

C. elegansbulk RNA-seq

𝕏 PostBluesky

Cell BiologyCommunications BiologyPeer-reviewedNov 24, 2025

Distinct mechanisms of non-autonomous UPRER mediated by GABAergic, glutamatergic, and octopaminergic neurons.

Aeowynn J. Coakley, Adam J. Hruby, Jing Wang…·Ryo Higuchi‐Sanabria

The paper identifies distinct roles of GABAergic, glutamatergic, and octopaminergic neurons in mediating non-autonomous UPRER through transcriptomic and functional analyses in C. elegans.

5 citations

C. elegansbulk RNA-seq

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Cell BiologyPLoS ONEPeer-reviewedSep 12, 2024

Mechanical stress through growth on stiffer substrates impacts animal health and longevity in C. elegans.

Maria Oorloff, Adam J. Hruby, Maxim Averbukh…·Ryo Higuchi‐Sanabria

This study investigates the impact of substrate stiffness on C. elegans health and longevity, finding only mild effects on cellular and organismal health.

6 citations

C. elegansexperimental assay

𝕏 PostBluesky