Author

Alain‐Pierre Petit

University of DundeeORCID 0009-0003-1016-6063Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

David W. GrayiD· 2 shared Fiona BellanyiD· 2 shared Paul K. FyfeiD· 2 shared Anthony G. Hope· 1 shared Catrina Kerr· 1 shared César Mendoza-MartíneziD· 1 shared Claire J. MackenzieiD· 1 shared Daniel A. Fletcher· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiochemistry

David W. GrayORCID

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2 papers

Recent·Most cited

BiochemistryBiochemical JournalPeer-reviewedJan 27, 2025

Characterisation of RNA guanine-7 methyltransferase (RNMT) using a small molecule approach

Lesley-Anne Pearson, Alain‐Pierre Petit, César Mendoza-Martínez…·David W. Gray

This study characterizes small molecule inhibitors of the HsRNMT-RAM complex, showing competitive binding and uncompetitive inhibition of RNA cap methylation.

8 citations

humanprotein structure

𝕏 PostBluesky

Pharmacology & ToxicologyChemMedChemPeer-reviewedApr 6, 2024

Application of an NMR/crystallography fragment screening platform for the assessment and rapid discovery of new HIV-CA binding fragments

Stuart Lang, Daniel A. Fletcher, Alain‐Pierre Petit…·David W. Gray

The paper uses NMR and crystallography to identify and assess new HIV-CA binding fragments, leading to the discovery of two compounds with improved binding properties.

1 citation

experimental assaydrug response / drug discovery

𝕏 PostBluesky