Marije Been

This study identifies excessive RAS/MAPK pathway activation as a cause of adult-onset motor axonal degeneration in Drosophila, showing that inhibiting the pathway can rescue neurodegenerative phenotypes.

The paper identifies polyamine metabolism genes that converge with RASopathies on RAS/MAPK and sensory processing phenotypes in Drosophila.

This study identifies FUS's role in muscle differentiation and structure through phase separation-mediated recruitment of ETV5 and MEF2, showing its dysfunction in FUS-ALS.

The paper shows that TORC1 and PKA activity related to ribosome biogenesis oscillates with the budding yeast cell cycle under constant conditions.

This study shows that the Drosophila FUS ortholog cabeza regulates founder myoblast selection via Xrp1-dependent FGF signaling, affecting muscle development.