Author

Hongxiang Huang

Duke UniversityORCID 0009-0003-1558-1231Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Hongxia WangiD· 1 shared Huishan TaoiD· 1 shared John W. SleasmaniD· 1 shared Lei LiiD· 1 shared Michael B. FessleriD· 1 shared Peer W. F. KarmausiD· 1 shared Shimeng ZhangiD· 1 shared Xiao‐Ping ZhongiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

Hongxia WangORCID

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1 paper

Recent·Most cited

ImmunologyeLifePeer-reviewedSep 18, 2026

DGKα and ζ Deficiency Causes Regulatory T-Cell Dysregulation, Destabilization, and Conversion to Pathogenic T-Follicular Helper Cells to Trigger IgG1-Predominant Autoimmunity

Lei Li, Hongxiang Huang, Hongxia Wang…·Xiao‐Ping Zhong

This study shows that DGKα and ζ deficiency in Tregs leads to their dysfunction, conversion to pathogenic Tfh cells, and triggers IgG1-predominant autoimmunity.

3 citations

mouseexperimental assay

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