Author

Xiao‐Ping Zhong

Duke UniversityORCID 0000-0002-4619-8783Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Huishan TaoiD· 2 shared Yun PaniD· 2 shared Hongxia WangiD· 1 shared Hongxiang HuangiD· 1 shared Jinhai Xie· 1 shared John W. SleasmaniD· 1 shared Lei LiiD· 1 shared Michael B. FessleriD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Huishan TaoORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 12, 2026

Diacylglycerol Kinases Balance DAG Signaling to Control B Cell Maturation, Germinal Center Homeostasis, and Humoral Immunity

Jinhai Xie, Shimeng Zhang, Wendy Lee…·Xiao‐Ping Zhong

This study shows that diacylglycerol kinases regulate B-cell development and humoral immunity by modulating DAG signaling, with distinct effects on GC B-cell homeostasis and antibody responses.

DOI 10.64898/2026.10.05.756823

mouseexperimental assay

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ImmunologyeLifePeer-reviewedSep 18, 2026

DGKα and ζ Deficiency Causes Regulatory T-Cell Dysregulation, Destabilization, and Conversion to Pathogenic T-Follicular Helper Cells to Trigger IgG1-Predominant Autoimmunity

Lei Li, Hongxiang Huang, Hongxia Wang…·Xiao‐Ping Zhong

This study shows that DGKα and ζ deficiency in Tregs leads to their dysfunction, conversion to pathogenic Tfh cells, and triggers IgG1-predominant autoimmunity.

3 citations

mouseexperimental assay

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