Elizabeth C. McCulla

This study identifies Abi-1-S323 phosphorylation as a biomarker for DNA repair states and treatment response in cancers, showing its role in regulating radiosensitivity through Rac1 and CHK1 signaling.

This study recharacterizes RSL3 as a broad selenoprotein inhibitor, showing its potential as a therapeutic target for colorectal cancer by inducing ferroptosis.

This study shows pericyte-tumor interactions promote metastatic tumor cell dormancy via PIEZO1-mediated lysophospholipid transfer, enhancing persistence and relapse risk.

This study develops a method to culture pericytes under physiological oxygen conditions, preserving their phenotypes and enabling functional studies in health and disease.