Author

Izabella N. Castillo

University of North Carolina at Chapel HillORCID 0009-0003-2815-2807Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Organism:virus· 1

Frequent Co-Authors

Lakshmanane PremkumariD· 3 shared Ralph Steven BariciD· 2 shared Alba GrifoniiD· 1 shared Alessandro SetteiD· 1 shared Allison SeegeriD· 1 shared Amparo Martínez-PéreziD· 1 shared Andrew K. I. FalconariD· 1 shared Ángel BalmasedaiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersImmunology

Lakshmanane PremkumarORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedJul 1, 2025

Identification of immunogenic and cross-reactive chikungunya virus-specific CD4+ T cell epitopes in chronic chikungunya viral arthritic disease in humans

Rimjhim Agarwal, Calvin Ha, Fernanda Heloise Côrtes…·Daniela Weiskopf

This study identifies CD4+ T cell epitopes in chronic chikungunya virus disease, revealing conserved epitopes across alphaviruses and providing tools for T cell response analysis.

11 citations

humanproteomics

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MicrobiologyJournal of VirologyPeer-reviewedApr 16, 2025

Stabilized dengue virus 2 envelope subunit vaccine redirects the neutralizing antibody response to all E-domains

Devina Thiono, Demetrios Samaras, Thanh T.N. Phan…·Aravinda M. de Silva

This study evaluates a stabilized DENV2 E homodimer vaccine, finding it elicits broader neutralizing antibody responses targeting multiple E protein domains compared to the wild-type monomer.

6 citations

virusproteomics

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ImmunologyCell Reports MedicinePeer-reviewedAug 1, 2024

Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination

William N. Voss, Michael L. Mallory, Patrick O. Byrne…·Gregory C. Ippolito

This study compares IgG antibody responses from SARS-CoV-2 infection, vaccination, and hybrid immunity, finding that hybrid immunity retains the imprint of the initial exposure and enhances antibody breadth and affinity.

48 citationstop 1%

humanproteomics

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