Author

Paul D. Toth

The Ohio State UniversityORCID 0009-0003-3814-7657Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Bingcheng Wang· 1 shared Elena SeiradakeiD· 1 shared Elijah H. DayiD· 1 shared Soyeon Kim· 1 shared Steffen LindertiD· 1 shared Wei J. WangiD· 1 shared Xiaojun ShiiD· 1 shared Zachary C. DrakeiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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1 shared paperBiophysics

Bingcheng Wang

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJul 31, 2025

EphA2 and Ephrin-A1 Use the Same Interface for Both in cis and in trans Interactions That Regulate Distinct Cell Signaling and Function

Soyeon Kim, Paul D. Toth, Wei J. Wang…·Bingcheng Wang

This paper identifies a shared interface for EphA2-ephrin-A1 cis and trans interactions, showing cis interactions inhibit trans signaling and contribute to oncogenesis.

1 citation

humanproteomics

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BiochemistryNature CommunicationsPeer-reviewedJul 25, 2025

Deep-Learning Structure Elucidation from Single-Mutant Deep Mutational Scanning

Zachary C. Drake, Elijah H. Day, Paul D. Toth, Steffen Lindert

This paper introduces DMS-Fold, a method that uses deep mutational scanning data to improve AlphaFold2 predictions, achieving better results for most protein targets.

14 citations

protein structuredeep learning

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