Author

Lauren D’Sa

Papworth Hospital NHS Foundation TrustORCID 0009-0003-4224-2622Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Ali Önder YildirimiD· 1 shared Alice Chernaik· 1 shared Anne HilgendorffiD· 1 shared Christina Gabriel· 1 shared Daniella Black· 1 shared Frank M. McCaughaniD· 1 shared Helen Davies· 1 shared Holly A. R. Giles· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ali Önder YildirimORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintSep 18, 2026

Carcinogen-induced preinvasive human squamous lung cancer is characterised by a novel atypical basal cell state and presents opportunities for chemoprevention

Wenrui Guo, Holly A. R. Giles, Alice Chernaik…·Frank M. McCaughan

This study develops a human model of early squamous lung cancer induced by a carcinogen, identifies a novel atypical basal cell state, and shows that capivasertib prevents and reverses the abnormal phenotype.

DOI 10.64898/2026.09.17.748423

humanbulk RNA-seq

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