Author

Helen Davies

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniella Black· 2 shared Serena Nik‐ZainaliD· 2 shared Yasin MemariiD· 2 shared Ali Önder YildirimiD· 1 shared Alice Chernaik· 1 shared Andrea DegasperiiD· 1 shared Andrew N.J. TuttiD· 1 shared Anne HilgendorffiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenomics

Daniella Black

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Global signatures of Ribonucleotide Excision Repair deficiency and its therapeutic vulnerabilities

Ping Jing Toong, Soraya Boushaki, Salome Jingchen Zhao, Rachel Brough, Fei Song, Dragomir B. Krastev, Daniella Black, Giuseppe Rinaldi, Cherif Badja, Andrea Degasperi, Jan Czarnecki, Yasin Memari, Helen Davies, Daniel Hüebschmann, Hanno Glimm, , Serena Nik‐Zainal

This study identifies RER deficiency as a new DNA repair defect in cancer, detectable through mutational signatures and linked to therapeutic vulnerabilities.

bioRxiv · Oct 15, 2026 · PreprintGenomics

Carcinogen-induced preinvasive human squamous lung cancer is characterised by a novel atypical basal cell state and presents opportunities for chemoprevention

Wenrui Guo, Holly A. R. Giles, Alice Chernaik, Yasin Memari, Joanna Xie, Daniella Black, Anne Hilgendorff, Christina Gabriel, Ali Önder Yildirim, Helen Davies, Martin Goddard, Lauren D’Sa, Otmar Schmid, Serena Nik‐Zainal, Namshik Han, Frank M. McCaughan

This study develops a human model of early squamous lung cancer induced by a carcinogen, identifies a novel atypical basal cell state, and shows that capivasertib prevents and reverses the abnormal phenotype.

bioRxiv · Sep 18, 2026 · PreprintCancer Biology