Author
Surrozen, Inc. (United States)ORCID 0009-0003-4786-7453Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Russell B. Fletcher, Hui Chen, Yorick Post…·Yang Li
The paper develops a bispecific antibody targeting TGFBR2 on human fibroblasts, showing cell selectivity and enhanced potency while avoiding systemic toxicity.
Parthasarathy Sampathkumar, Heekyung Jung, Hui Chen…·Yang Li
The paper describes the development of new antibodies that enhance Wnt signaling through targeted protein degradation by sequestering E3 ligases.
Hui Chen, Sung‐Jin Lee, Ryan Li…·Yang Li
The paper introduces a cell-specific targeting strategy called BRAID, validated using the WNT/{beta}-catenin system, showing it can induce signaling specifically on hepatocytes.