Author

Adrienne N. Santiago

Columbia UniversityORCID 0000-0002-5022-1675Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Organism:rat· 1

Frequent Co-Authors

Phi T. NguyeniD· 2 shared René HeniD· 2 shared Chiye J. AokiiD· 1 shared Elizabeth I. FlandreauiD· 1 shared Emily A MakowicziD· 1 shared Erin HernandeziD· 1 shared Eva M GeogheganiD· 1 shared Hannah M. Chung· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Phi T. NguyenORCID

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Author profile →

3 papers

Recent·Most cited

The Converging Effects of Different Categories of Antidepressants on the Brain: A Systematic Meta-Analysis of Public Transcriptional Profiling Data from the Hippocampus and Cortex

Eva M Geoghegan, Megan Hastings Hagenauer, Erin Hernandez, Sophia Espinoza, Elizabeth I. Flandreau, Phi T. Nguyen, Adrienne N. Santiago, Mubashshir Ra'eed Bhuiyan, Sophie Mensch, Stanley J. Watson, Huda Akil, René Hen

This paper performs two meta-analyses of transcriptional data from rodent brain regions to identify shared gene expression changes across antidepressant categories.

Journal of Neurochemistry · Jul 1, 2026Peer-reviewedNeuroscience

Effects of electroconvulsive shock on the function, circuitry, and transcriptome of dentate gyrus granule neurons

Adrienne N. Santiago, Julia Castello Saval, Phi Nguyen, Hannah M. Chung, Shaharia Khan, Victor M. Luna, René Hen, Wei-li Chang

This study shows ECS-induced neurogenesis is necessary for antidepressant effects and identifies transcriptomic changes in granule neurons.

Neuropsychopharmacology · Feb 4, 2026Peer-reviewedNeuroscience

Food restriction engages prefrontal corticostriatal cells and local microcircuitry to drive the decision to run vs conserve energy

Adrienne N. Santiago, Emily A Makowicz, Muzi Du, Chiye J. Aoki

The paper shows that specific prefrontal cortex cells control running behavior during food restriction, revealing a causal role in energy conservation decisions.

Cerebral Cortex · Dec 10, 2020Peer-reviewedNeuroscience