Author

John P. McGinnis

Baylor College of MedicineORCID 0009-0003-5669-5913Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Benjamin D. W. BelfortiD· 3 shared Benjamin Russell ArenkieliD· 3 shared Joshua Ortiz‐GuzmaniD· 3 shared Akdes Serin HarmancıiD· 2 shared Ali JalaliiD· 2 shared Angela Patricia AddisoniD· 2 shared Carrie MohilaiD· 2 shared Daniel J. CurryiD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Benjamin D. W. BelfortORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BioengineeringMolecular Therapy — Methods & Clinical DevelopmentPeer-reviewedMay 21, 2025

Common AAV gene therapy vectors show indiscriminate transduction of living human brain cell types

John P. McGinnis, Joshua Ortiz‐Guzman, Maria Camila Guevara…·Benjamin Russell Arenkiel

This study shows common AAV vectors transduce multiple human brain cell types in organotypic slices, with astrocytes showing the most protein expression, and introduces a pipeline for optimizing AAV vectors.

6 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeuroscienceFrontiers in NeurosciencePeer-reviewedFeb 13, 2025

Comparative Analysis of AAV Serotypes for Transduction of Olfactory Sensory Neurons

Benjamin D. W. Belfort, Johnathan D. Jia, Alexandra R Garza…·Benjamin Russell Arenkiel

This study compares 11 AAV serotypes for transduction efficiency and specificity in murine olfactory sensory neurons using nasal inoculation.

DOI 10.3389/fnins.2025.1531122

mousebulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintDec 19, 2024

Cell type transcriptional identities are maintained in cultured ex vivo human brain tissue

John P. McGinnis, Joshua Ortiz‐Guzman, Sai Mallannagari…·Benjamin Russell Arenkiel

The paper evaluates the transcriptional stability of cell types in ex vivo human brain tissue cultures over 14 days using single-nucleus RNA sequencing.

2 citations

humanscRNA-seq

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