Maria G. Tettamanti

The paper identifies atonosomes as tension-responsive plasma membrane-derived compartments in yeast, showing they form rapidly in response to membrane tension loss and are regulated by cell wall dynamics.

This study determines the cryo-EM structure of yeast TORC2, revealing how phosphoinositides activate it through structural rearrangements involving regulatory subunits.

The paper shows that TORC2 regulates sterol redistribution to recover from membrane perturbation by small amphipathic molecules in yeast and mammalian cells.

This study identifies the Dsc ubiquitin ligase complex as a quality control mechanism at the Golgi that degrades orphaned proteins by assessing transmembrane domain hydrophobicity.