Author

Gijs-Jan Scholten

Radboud University Medical CenterORCID 0009-0003-7467-1894Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metabolomics· 1

Frequent Co-Authors

Alejandro GarantoiD· 2 shared Astrid R. Oudakker· 2 shared Clara van KarnebeekiD· 2 shared Dirk J. LefeberiD· 2 shared Imke M. E. SchuurmansiD· 2 shared Nael Nadif KasriiD· 2 shared Sofía PuvogeliD· 2 shared Amalia M. DolgaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Alejandro GarantoORCID

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2 papers

Recent·Most cited

NeurosciencePure Amsterdam UMCPeer-reviewedSep 1, 2026

Navigating Human Astrocyte Differentiation: Direct and Rapid one-step Differentiation of Induced Pluripotent Stem Cells to Functional Astrocytes Supporting Neuronal Network development

Imke M. E. Schuurmans, Annika Mordelt, Marta Guevara‐Ferrer…·Nael Nadif Kasri

This study presents a one-step protocol to differentiate hiPSCs into functional astrocytes, enabling co-culture with neurons to support network development.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologyMolecular Therapy — Nucleic AcidsPeer-reviewedOct 1, 2025

Targeting AASS improves neurotoxicity and mitochondrial function in astrocyte models for pyridoxine dependent epilepsy

Imke M. E. Schuurmans, Udo F. H. Engelke, Muna Abedrabbo…·Alejandro Garanto

This study shows that targeting AASS in astrocytes reduces neurotoxicity and improves mitochondrial function in a model of pyridoxine-dependent epilepsy.

5 citations

humanbulk RNA-seq

𝕏 PostBluesky