Chaitra Sreenivasaiah

Patient-derived IgG Amplifies Fcγ Receptor-Dependent Colonic Inflammation During Immune Checkpoint Blockade

The paper shows that patient-derived IgG from those with severe immune-related colitis amplifies inflammation during immune checkpoint blockade in humanized FcγR mice.

Atypical memory B cells contribute to heterogeneous vaccine responses in ocrelizumab-treated patients with multiple sclerosis

The paper examines how B-cell subsets in ocrelizumab-treated multiple sclerosis patients influence vaccine responses to SARS-CoV-2, identifying specific B-cell populations associated with immune response variability.

Dicer is essential for proper maturation, composition, and function in the postnatal retina.

The paper shows that Dicer/miRNAs in late retinal progenitor cells are essential for proper postnatal retinal development and function.