Pharmacology & ToxicologyAngewandte Chemie International EditionPeer-reviewed
Covalent activation of the C-type lectin DC-SIGN
Jonathan Lefèbre, Maurice Besch, Noémi Csorba…·Christoph Rademacher
This paper identifies two covalent activators of DC-SIGN by screening a lysine-targeted electrophilic fragment library, revealing distinct mechanisms of activation through structural and functional analyses.
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