Author
University of ViennaORCID 0000-0001-8505-2181Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Chuanhao Peng, Simatsidk Haregu, Claire Yi-Ling Yang…·Ratmir Derda
The paper evaluates how glycan-binding proteins and immune cells recognize mirror-image glycans, finding widespread binding and donor-specific recognition of L-glycans.
Jonathan Lefèbre, Maurice Besch, Marcelo Daniel Gamarra…·Christoph Rademacher
The paper identifies a cryptic allosteric pocket in DC-SIGN that modulates oligosaccharide binding through conformational changes and residue mutations.
Jonathan Lefèbre, Maurice Besch, Noémi Csorba…·Christoph Rademacher
This paper identifies two covalent activators of DC-SIGN by screening a lysine-targeted electrophilic fragment library, revealing distinct mechanisms of activation through structural and functional analyses.