Author

Zachary R. Russell

Fred Hutch Cancer CenterORCID 0009-0003-9659-6389Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Eric C. HollandiD· 3 shared Frank SzulzewskyiD· 3 shared Abigail G. ParrishiD· 1 shared Aleena K. S. ArakakiiD· 1 shared Alex Shimura YamashitaiD· 1 shared Betemariyam N. Gessesse· 1 shared David C. Quist· 1 shared Debra K. Kumasaka· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

Eric C. HollandORCID

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3 papers

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedFeb 10, 2026

A Systems approach identifies MERTK as a therapeutic vulnerability in ZFTA-RELA-driven ependymomas

Marina Chan, Songli Zhu, Zachary R. Russell…·Taranjit S. Gujral

This study identifies MERTK as a therapeutic target in ZFTA-RELA-driven ependymomas through transcriptomic analysis and drug screening.

2 citations

humanbulk RNA-seq

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Cancer BiologySciencePeer-reviewedFeb 13, 2025

RNA Polymerase II hypertranscription at histone genes in cancer FFPE samples

Steven Henikoff, Ye Zheng, Ronald M. Paranal…·Kami Ahmad

The paper identifies RNA Polymerase II hypertranscription at histone genes in cancer FFPE samples, linking it to tumor progression and aneuploidy.

52 citationstop 1%

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Cancer BiologyCell ReportsPeer-reviewedOct 1, 2024

ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models.

Sebastian Schmid, Zachary R. Russell, Alex Shimura Yamashita…·Frank Szulzewsky

This study shows ERK signaling promotes resistance to TRK inhibitors in NTRK fusion-driven glioma mouse models and suggests MEK inhibition as a potential combination therapy.

9 citations

mouseexperimental assay

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