Author

Elena S. Klimtchuk

Boston UniversityORCID 0009-0004-0254-0550Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Gareth J. MorganiD· 2 shared Andrew StaroniD· 1 shared Bindu Y. SrinivasuiD· 1 shared Camille Vanessa EdwardsiD· 1 shared Daniele PeterleiD· 1 shared Derek J. RhoadesiD· 1 shared Feiya WangiD· 1 shared Frederick L. RubergiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

Gareth J. MorganORCID

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2 papers

Recent·Most cited

BiophysicsJournal of Molecular BiologyPeer-reviewedJun 29, 2026

Small molecule stabilization of diverse amyloidogenic immunoglobulin light chains revealed by hydrogen-deuterium exchange mass spectrometry

Daniele Peterle, N. Yan, Elena S. Klimtchuk…·Gareth J. Morgan

This study identifies small molecules that stabilize diverse amyloidogenic immunoglobulin light chains by reducing conformational dynamics and proteolysis.

2 citations

proteomicsexperimental assay

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Cell BiologyAmyloidPeer-reviewedMar 25, 2025

Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition

Camille Vanessa Edwards, Grace M. Ferri, Josue Villegas-Galaviz…·George J. Murphy

The paper identifies early molecular and functional signatures in cardiac AL amyloidosis patients with abnormal GLS and reduced inflammatory markers despite no significant amyloid fibril deposition.

5 citations

humanbulk RNA-seq

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