Cell BiologybioRxivPreprint
LplA-mediated rescue of lethal myopathy and cardiomyopathy in mitochondrial lipoylation-deficient mammalian caused by Lipt1
Junru Yu, Zhijuan Hu, Ziwei Liu…·Anping Zeng
This study uses AAV-delivered LplA to rescue lethal mitochondrial lipoylation defects in Lipt1-deficient mice, improving survival, motor function, and cardiac health.
DOI 10.64898/2026.11.01.761485