Janett Piesker

The EMT transcription factor Snai1 maintains myocardial wall integrity by repressing intermediate filament gene expression

This study identifies Snai1's role in maintaining myocardial wall integrity by repressing intermediate filament gene expression in zebrafish.

Endothelial TGF-β signaling instructs smooth muscle development in the cardiac outflow tract

This study shows that endothelial TGF-β signaling is crucial for cardiac outflow tract development, as its disruption leads to OFT dilation and SMC disorganization, which can be partially rescued by fibulin-5 modulation.

Integration of multiple imaging platforms to uncover cardiac defects in adult zebrafish

The paper combines multiple imaging techniques to detect cardiac defects in adult zebrafish that were previously undetectable.

Cardiac valve regeneration in adult zebrafish: importance of TGF-β signaling in new tissue formation

This study shows adult zebrafish can regenerate cardiac valves after decellularization, with TGF-β signaling promoting this process by enhancing progenitor cell proliferation and differentiation.