Christian SM Helker

This study shows Apelin signaling is essential for Vegfc-Vegfr3-dependent lymphatic sprouting and promotes LEC migration.

This study identifies Svep1 as a factor that stabilizes vascular anastomosis in zebrafish embryos under reduced flow conditions.

This study shows that endothelial TGF-β signaling is crucial for cardiac outflow tract development, as its disruption leads to OFT dilation and SMC disorganization, which can be partially rescued by fibulin-5 modulation.

The paper combines multiple imaging techniques to detect cardiac defects in adult zebrafish that were previously undetectable.

This study shows adult zebrafish can regenerate cardiac valves after decellularization, with TGF-β signaling promoting this process by enhancing progenitor cell proliferation and differentiation.

The paper identifies insulin-independent modulators of glucose metabolism using a zebrafish model and finds androgen receptor antagonists reduce fasting glucose levels in insulin mutants.