Author

Hiroshi Sakamoto

Ehime UniversityORCID 0009-0004-0876-7449Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Organism:mouse· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Akiyasu IwaseiD· 1 shared Daisuke ShiokawaiD· 1 shared Hiroki KuriharaiD· 1 shared Hironori IzutaniiD· 1 shared Hirotsugu KurobeiD· 1 shared Mie KurataiD· 1 shared Mika HamaguchiiD· 1 shared Osamu YamaguchiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Akiyasu IwaseORCID

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1 paper

Recent·Most cited

Stromal CTHRC1 protects the valvular interstitium from macrophage-associated inflammatory remodeling and calcification

Hiroshi Sakamoto, Tomohisa Sakaue, Mika Hamaguchi, Yasuhisa Nakao, Mie Kurata, Akiyasu Iwase, Hiroki Kurihara, Yosuke Kiriyama, Takuma Fukunishi, Hirotsugu Kurobe, Takashi Nishimura, Shunji Uchita, Daisuke Shiokawa, Yoshiaki Kubota, Osamu Yamaguchi, Hironori Izutani

This study identifies CTHRC1 as a protective factor in valvular interstitium that limits macrophage-driven calcification in aortic valve disease.

bioRxiv · Sep 25, 2026 · PreprintMolecular Biology