Hiroki Kurihara

Stromal CTHRC1 protects the valvular interstitium from macrophage-associated inflammatory remodeling and calcification

This study identifies CTHRC1 as a protective factor in valvular interstitium that limits macrophage-driven calcification in aortic valve disease.

Hox-Meis-relayed gene regulatory transition underlies cardiopharyngeal neural crest diversification

The paper maps lineage trajectories and gene regulatory networks of cardiopharyngeal neural crest cells in mice, identifying a Hox-Meis-regulated transition associated with cardiac cushion development.

The cardiopharyngeal mesoderm contributes to lymphatic vessel development

This study identifies the cardiopharyngeal mesoderm as a non-venous source of lymphatic endothelial cells contributing to craniofacial and cardiac lymphatic networks.

Cardiac neural crest lineage diversity and underlying gene regulatory networks revealed by multimodal analysis

The paper uses multimodal analysis to reveal cardiac neural crest lineage diversity and gene regulatory networks involved in their differentiation.

Lysine demethylase 7a regulates the anterior-posterior development in mouse by modulating the transcription of Hox gene cluster

This study shows that Kdm7a regulates posterior Hox gene expression in mouse embryos by demethylating H3K9me2, leading to anterior-posterior developmental defects.

Probing the origin of matching functional jaws: roles of Dlx5/6 in cranial neural crest cells.

The paper investigates the role of Dlx5/6 in cranial neural crest cells in determining jaw identity and symmetry, showing that their expression in NCCs is critical for lower jaw development and jaw matching.