Rui Mamede Branca

This study compares proteomic profiles of steady-state and cultured human erythroid progenitors, revealing how culture-induced stress alters protein expression and erythroid maturation dynamics.

This study identifies how RNA splicing factor mutations drive myeloid neoplasm by disrupting proteomic networks through mis-splicing, validated via single-cell transcriptomics and proteomics.

The paper uses pooled overexpression screens to identify PIPPI, a novel microprotein involved in the ER stress response, by screening sORFs for cytoprotective effects against 6-thioguanine.

This study identifies a non-canonical ovarian tumor peptide that induces memory-like features in NK cells through HLA-E engagement and receptor interaction.

This study shows mitochondrial dysfunction causes liver lipid accumulation and inflammation in mtDNA mutator mice without obesity or insulin resistance.

The paper introduces tools to generate proteogenomics databases using ENSEMBL resources, revealing non-canonical peptides in public datasets.