Earl G. Brown

Elevated phosphorylated α-synuclein and phosphorylated tau in Lrrk2 p.G2019S-mutant mice following influenza A pneumonitis

This study shows that Lrrk2 p.G2019S mutant mice exhibit increased phosphorylated α-synuclein and tau in the brain after influenza A infection, suggesting a link between LRRK2 mutations and neurodegeneration.

Variants in Lrrk2 and Snca deficiency do not alter the course of primary encephalitis due to neurotropic reovirus T3D in newborn mice

This study shows that Lrrk2 and Snca gene variants do not affect encephalitis severity in newborn mice infected with reovirus T3D via direct brain inoculation, unlike intranasal infection.

A Protocol for Neuralized Murine Olfactory Organoids

This paper presents a method to generate olfactory organoids from adult mice to study environmental interactions with the olfactory epithelium and disease processes.