Author

Lisa Aziez

Centre National de la Recherche ScientifiqueORCID 0009-0004-1840-6698Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Assay:clinical cohort / trial· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Yannick SimoniiD· 3 shared Cyril CatelainiD· 2 shared Didier BouscaryiD· 2 shared Dorothée Selimoglu‐BuetiD· 2 shared Ismaël BoussaidiD· 2 shared Justine DecroocqiD· 2 shared Marguerite VignoniD· 2 shared Michaëla FontenayiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Yannick SimoniORCID

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Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivPreprintAug 21, 2026

Integration of clinical and T-cell immune profiling to predict early response to CD3xBCMA bispecific antibody immunotherapy in Multiple Myeloma

Nicolas Deredec, Lisa Aziez, Ismaël Boussaid…·Yannick Simoni

This study integrates clinical and T-cell immune profiling to identify early biomarkers of response to CD3xBCMA bispecific antibody therapy in multiple myeloma.

DOI 10.64898/2026.08.17.743749

humanclinical cohort / trial

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ImmunologyMolecular TherapyPeer-reviewedApr 4, 2026

An in vivo CRISPR screen unveils top target genes to improve CAR-T cell efficacy in a solid tumor model

Mattia Fumagalli, Dongjie An, Luca Simula…·Frédéric Pendino

This study uses an in vivo CRISPR screen to identify genes that enhance CAR-T cell efficacy in a solid tumor model, finding that disrupting REGNASE-1, SOCS1, PTPN2, and P16/NK4A improves tumor eradication.

4 citationstop 1%

humangenetic perturbation / CRISPR

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ImmunologybioRxivPreprintAug 12, 2025

Pro-inflammatory role of granzyme K producing bystander CD8+ T cells in acute myeloid leukemia

Lisa Aziez, Nicolas Deredec, Ismaël Boussaid…·Yannick Simoni

This study identifies a pro-inflammatory role of Granzyme K-producing bystander CD8+ T cells in AML, which promote IL-8 secretion and may exacerbate disease progression.

DOI 10.1101/2025.08.12.669682

humanflow cytometry

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