Jonathan N.V. Martinson

The paper investigates how motility affects cross-feeding mutualisms between E. coli and S. enterica, finding that spatial structure and metabolic dynamics determine the selective advantage of motility.

The paper shows conjugative plasmids eliminate non-permissive bacterial recipients through lethal zygosis, enabling their own spread and improving gene editing efficiency with shielded transposon vectors.

This study identifies host factors that influence VchCAST activity and demonstrates that the λ-Red recombineering system significantly enhances its editing efficiency in E. coli and other bacteria.

OriGen generates and validates new plasmid origins of replication, demonstrating its ability to create functional sequences distinct from existing wild types.