Taylor E. Senay

This study shows neurotropic L. monocytogenes strains preferentially invade enteric glial cells in the gut, using actin-based motility to spread to neurons and potentially reach the brainstem.

The paper identifies a short intrinsically disordered domain in MCPyV ALTO, LIT, that regulates TBK1 signaling and MCPyV latency by inhibiting TBK1 activation.

This study identifies MCPyV protein ALTO as a factor that modulates the STING-TBK1 pathway to limit viral replication and maintain persistent infection.