Author

Ziyang Xiao

University of Wisconsin–MadisonORCID 0009-0004-2537-0777Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

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Approach:biophysical modeling· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Abha JainiD· 1 shared Arnab Das· 1 shared Craig E. CameroniD· 1 shared David DuliniD· 1 shared Jamie J. ArnoldiD· 1 shared Robert N. KirchdoerferiD· 1 shared Thomas K. AndersoniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Abha JainORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintAug 26, 2025

The 2'-endo conformation of arabinose-CTP and arabinose-UTP inhibit viral polymerases by inducing long pauses.

Ziyang Xiao, Arnab Das, Abha Jain…·Robert N. Kirchdoerfer

This study shows that arabinose nucleotides inhibit SARS-CoV-2 and poliovirus polymerases by causing long pauses due to the 2'-endo conformation of the incorporated nucleotides.

DOI 10.1101/2025.08.26.672356

proteomicsstructural biology

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