Cell BiologybioRxivPreprint
Lipid transfer by ORP3 is required for the regulation of PI4P and PI(4,5)P2 at the plasma membrane in mitosis
Anaïs Vertueux, Agathe Verraes, Christie Ouaddi…·Jean‐Marc Verbavatz
This study shows that ORP3 lipid transfer is essential for regulating PI4P and PI(4,5)P2 levels at the plasma membrane during mitosis, affecting cell division and preventing genetic instability.
DOI 10.1101/2025.10.22.684039