Author

Mélina L. Heuzé

Centre National de la Recherche ScientifiqueORCID 0000-0002-4271-2706Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Agathe VerraesiD· 1 shared Anaïs VertueuxiD· 1 shared Andrew P. KowalczykiD· 1 shared Cathy L. JacksoniD· 1 shared Christie OuaddiiD· 1 shared Cory L. SimpsoniD· 1 shared Emilie PellieriD· 1 shared Hugo SiegfriediD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

Agathe VerraesORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cadherin Regulation of Endoplasmic Reticulum-Plasma Membrane Contact Sites

Sonam Lhamo, Navaneetha Krishnan Bharathan, W. Giang, Kandice R. Levental, Cory L. Simpson, Stephanie Elaine Zimmer, Thomas Saba, Julie Beaucousin, Mélina L. Heuzé, Andrew P. Kowalczyk

This study shows that E-cadherin mediates ER recruitment to cell-cell junctions, forming ER-PMCS and integrating mechanical and lipid homeostasis.

Cell Reports · Jun 27, 2026Peer-reviewedCell Biology

Lipid transfer by ORP3 is required for the regulation of PI4P and PI(4,5)P2 at the plasma membrane in mitosis

Anaïs Vertueux, Agathe Verraes, Christie Ouaddi, Hugo Siegfried, Emilie Pellier, Véronique Proux‐Gillardeaux, Laurence Walch, Mélina L. Heuzé, Cathy L. Jackson, Jean‐Marc Verbavatz

This study shows that ORP3 lipid transfer is essential for regulating PI4P and PI(4,5)P2 levels at the plasma membrane during mitosis, affecting cell division and preventing genetic instability.

bioRxiv · Oct 22, 2025 · PreprintCell Biology