NeurosciencebioRxivPreprint
Low dose of a non-urea selective GIRK channel activator improves hippocampal-dependent synaptic plasticity and memory disrupted by amyloid-β oligomers
Jaime Mulero‐Franco, Raquel Jiménez‐Herrera, Ana Contreras…·Juan D. Navarro‐López
The paper tests a GIRK channel activator in AD models, finding low doses improve synaptic plasticity and memory without sex differences, while high doses impair function in healthy mice.
DOI 10.1101/2024.11.05.622060